Antibodies in solution: A LINXS-NIST Webinar Series
This Webinar Series is meant as an educational venture addressed to a broad audience including students and researchers from various backgrounds and all those who are interested to dive into the fascinating world of antibody research and learn more about the use of scattering methods for this purpose.
The Antibodies in Solution: a LINXS – NIST Webinar Series provides background information related to the currently ongoing LINXS antibody research program. This is a concerted experimental and theoretical effort that aims to investigate the properties of monoclonal antibodies in solution, which comprise a major platform for potential drug candidates and are of high academic and pharmaceutical interest. An international consortium of researchers at academic institutions, research centers, NIST and Novartis has teamed up for this.
Didactical lectures given by members of the consortium on different experimental and theoretical topics that are highly relevant for state-of-the-art antibody research as well as insight from pharmaceutical industry will be broadcasted. A central aspect of the webinar series will be to illustrate the full power of neutron and X-ray scattering science that can be achieved in combination with complementary experimental methods and different unifying simulation techniques.
TIMELINE
Events will be created continuously from autumn 2022. Each webinar will run from 35 to 40 minutes followed by questions from the participants. We hope to record all the webinars so that they can be available on the LINXS website, under Educational material.
INFORMATION AND REGISTRATION
Please go to LINXS events to find each webinar with more information about both the facility and the speaker. Here you will also find a link to the Zoom registration page.
WEBINAR SCHEDULE (the schedule will be continuously updated)
2024
Wednesday Feb 7, 15.30-16.30 CET
Ralf Biehl, FZ Jülich, Germany
Title: Domain Motions: Protein Dynamics seen by Neutron Spinecho Spectroscopy
More information and recorded talk
Wednesday march 6, 15.30-16.30 CET
Yun Liu, NIST, USA
Title: Protein internal dynamics and their relationship with the protein stability
More information
Wednesday april 10, 15.30-16.30 CET
Robin Curtis, University of Manchester, UK
Title: Using static light scattering to understand protein-protein and protein-solvent interactions
More information and recorded talk
wednesday may 8, 15.30-16.30 CET
Christopher Roberts, University of Delaware, USA
Title: From Colloidal Self Interactions to Self-Association of Therapeutic Proteins: Combining Experimental & Computational Tools
More information and recorded talk
Thursday June 13, 15.30-16.30 CET
Margarita Kruteva, FZ Jülich, Germany
Title: Diffusion NMR to study dynamics of polymers and bio-macromolecules
More information and recorded talk
Wednesday Dec 18, 15.30-16.30 CET
Amy Xu, Louisiana State University, USA
Title: Characterizing Interactions and Conformational Flexibility of Monoclonal Antibodies Using Small-Angle Scattering
More information and registration
2023
Wednesday Feb 1, 15.30-16.30
Sergej Grudinin, CNRS, France
Title: Structural Bioinformatics in the era of AlphaFold
More information and recorded talk
Wednesday march 1, 15.30-16.30
John Marino, Nist, USA
Title: NMR
More information and recorded talk
Wednesday april 5, 15.30-16.30 Postponed
Ralf Biehl, Jülich Centre for Neutron Science (JCNS), Germany
Title: Domain Motions
More information
Wednesday May 3, 15.30-16.30
Mikael Lund, Lund University, Sweden
Title: Little-known Interactions Between Proteins
More information and recorded talk
Wednesday June 7, 15.30-16.30
Christina Bergonzo, Nist, USA
Title: All Atom MD
More information
Wednesday oct 11, 15.30-16.30
Peter Schurtenberger, Lund University, Sweden
Title: “Understanding the structure and dynamics of concentrated antibody solutions
- pros and cons of a colloid approach”
More information and recorded talk
Wednesday nov 1, 15.30-16.30
Roseanna Zia, Stanford University, USA
Title: Mesoscale Simulations
More information and recorded talk
Wednesday dec 6, 15.30-16.30
Harold “Wick” Hatch, Nist, USA
Title: CG Simulations
More information and recorded talk
2022
WEDNESDAY NOV 2, 15.30 - 16.30
Karoline Bechtold-Peters, NOVARTIS, Switzerland
Title: Therapeutical monoclonal antibodies - significance for patients and evolution into the future
More information and recorded talk
WEDNESDAY Dec 7, 15.30 - 16.30
John Schiel, Nist, USA
Title: NISTmAb and More: Standards and Technology Paved by the Community
More information and recorded talk